16,239 research outputs found

    Strongly interacting neutrinos as the highest energy cosmic rays

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    We show that all features of the ultrahigh energy cosmic ray spectrum from 10^{17} eV to 10^{21} eV can be described with a simple power-like injection spectrum of protons under the assumption that the neutrino-nucleon cross-section is significantly enhanced at center of mass energies above \approx 100 TeV. In our scenario, the cosmogenic neutrinos produced during the propagation of protons through the cosmic microwave background initiate air showers in the atmosphere, just as the protons. The total air shower spectrum induced by protons and neutrinos shows excellent agreement with the observations. A particular possibility for a large neutrino-nucleon cross-section exists within the Standard Model through electroweak instanton-induced processes.Comment: 8 pages, 4 figures, talk given at Beyond the Desert '03, Castle Ringberg, 9-14 June, 200

    Radiance and Doppler shift distributions across the network of the quiet Sun

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    The radiance and Doppler-shift distributions across the solar network provide observational constraints of two-dimensional modeling of transition-region emission and flows in coronal funnels. Two different methods, dispersion plots and average-profile studies, were applied to investigate these distributions. In the dispersion plots, we divided the entire scanned region into a bright and a dark part according to an image of Fe xii; we plotted intensities and Doppler shifts in each bin as determined according to a filtered intensity of Si ii. We also studied the difference in height variations of the magnetic field as extrapolated from the MDI magnetogram, in and outside network. For the average-profile study, we selected 74 individual cases and derived the average profiles of intensities and Doppler shifts across the network. The dispersion plots reveal that the intensities of Si ii and C iv increase from network boundary to network center in both parts. However, the intensity of Ne viii shows different trends, namely increasing in the bright part and decreasing in the dark part. In both parts, the Doppler shift of C iv increases steadily from internetwork to network center. The average-profile study reveals that the intensities of the three lines all decline from the network center to internetwork region. The binned intensities of Si ii and Ne viii have a good correlation. We also find that the large blue shift of Ne viii does not coincide with large red shift of C iv. Our results suggest that the network structure is still prominent at the layer where Ne viii is formed in the quiet Sun, and that the magnetic structures expand more strongly in the dark part than in the bright part of this quiet Sun region.Comment: 10 pages,9 figure

    Multiple regulatory domains on the Byr2 protein kinase

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    Byr2 protein kinase, a homolog of mammalian mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEKK) and Saccharomyces cerevisiae STE11, is required for pheromone-induced sexual differentiation in the fission yeast Schizosaccharomyces pombe. Byr2 functions downstream of Ste4, Ras1, and the membrane-associated receptor-coupled heterotrimeric G-protein alpha subunit, Gpa1. Byr2 has a distinctive N-terminal kinase regulatory domain and a characteristic C-terminal kinase catalytic domain. Ste4 and Ras1 interact with the regulatory domain of Byr2 directly. Here, we define the domains of Byr2 that bind Ste4 and Ras1 and show that the Byr2 regulatory domain binds to the catalytic domain in the two-hybrid system. Using Byr2 mutants, we demonstrate that these direct physical interactions are all required for proper signaling. In particular, the physical association between Byr2 regulatory and catalytic domains appears to result in autoinhibition, the loss of which results in kinase activation. Furthermore, we provide evidence that Shk1, the S. pombe homolog of the STE20 protein kinase, can directly antagonize the Byr2 intramolecular interaction, possibly by phosphorylating Byr2

    Event-specific chorus wave and electron seed population models in DREAM3D using the Van Allen Probes

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    Abstract The DREAM3D diffusion model is applied to Van Allen Probes observations of the fast dropout and strong enhancement of MeV electrons during the October 2012 double-dip storm. We show that in order to explain the very different behavior in the two dips, diffusion in all three dimensions (energy, pitch angle, and Lo) coupled with data-driven, event-specific inputs, and boundary conditions is required. Specifically, we find that outward radial diffusion to the solar wind-driven magnetopause, an event-specific chorus wave model, and a dynamic lower-energy seed population are critical for modeling the dynamics. In contrast, models that include only a subset of processes, use statistical wave amplitudes, or rely on inward radial diffusion of a seed population, perform poorly. The results illustrate the utility of the high resolution, comprehensive set of Van Allen Probes\u27 measurements in studying the balance between source and loss in the radiation belt, a principal goal of the mission. Key Points DREAM3D uses event-specific driving conditions measured by Van Allen Probes Electron dropout is due to outward radial diffusion to compressed magnetopause Event-specific chorus and seed electrons are necessary for the enhancement

    Spin 3/2 dimer model

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    We present a parent Hamiltonian for weakly dimerized valence bond solid states for arbitrary half-integral S. While the model reduces for S=1/2 to the Majumdar-Ghosh Hamiltonian we discuss this model and its properties for S=3/2. Its degenerate ground state is the most popular toy model state for discussing dimerization in spin 3/2 chains. In particular, it describes the impurity induced dimer phase in Cr8Ni as proposed recently. We point out that the explicit construction of the Hamiltonian and its main features apply to arbitrary half-integral spin S.Comment: 5+ pages, 6 figures; to appear in Europhysics Letter

    The interaction between stray electrostatic fields and a charged free-falling test mass

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    We present an experimental analysis of force noise caused by stray electrostatic fields acting on a charged test mass inside a conducting enclosure, a key problem for precise gravitational experiments. Measurement of the average field that couples to test mass charge, and its fluctuations, is performed with two independent torsion pendulum techniques, including direct measurement of the forces caused by a change in electrostatic charge. We analyze the problem with an improved electrostatic model that, coupled with the experimental data, also indicates how to correctly measure and null the stray field that interacts with test mass charge. Our measurements allow a conservative upper limit on acceleration noise, of 2 fm/s2^2\rthz\ for frequencies above 0.1 mHz, for the interaction between stray fields and charge in the LISA gravitational wave mission.Comment: Minor edits in PRL publication proces

    Outcomes of a remote, decentralized health center-based HIV/AIDS antiretroviral program in Zambia, 2003 to 2007

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    A cross-sectional study of patients living with HIV/ AIDS treated during 2003 to 2007 in decentralized, rural health centers in Zambia was performed to measure virological outcomes after 12 months of antiretroviral therapy and identify factors associated with virological failure. Data from 228 patients who started antiretroviral therapy >12 months prior were analyzed. In all, 93% received stavudine + lamivudine + nevirapine regimens, and median antiretroviral therapy duration was 23.5 months (interquartile range 20-28). Of the 205 patients tested for viral load, 177 (86%) had viral load <1000 copies/mL. Probability of developing virological failure (viral load >1000 copies/mL) was 8.9% at 24 months and 19.6% at 32 months. Predictors for virological failure were <100% adherence, body mass index <18.5 kg/m(2), and women <40 years old. Of those with virological failure who underwent 3 to 6 months of intensive adherence counseling, 45% obtained virological success. In a remote, resource-limited setting in decentralized health centers, virological and immunological assessments of patients on antiretroviral therapy >12 months showed that positive health outcomes are achievable

    Nonlinear elasticity of monolayer graphene

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    By combining continuum elasticity theory and tight-binding atomistic simulations, we work out the constitutive nonlinear stress-strain relation for graphene stretching elasticity and we calculate all the corresponding nonlinear elastic moduli. Present results represent a robust picture on elastic behavior of one-atom thick carbon sheets and provide the proper interpretation of recent experiments. In particular, we discuss the physical meaning of the effective nonlinear elastic modulus there introduced and we predict its value in good agreement with available data. Finally, a hyperelastic softening behavior is observed and discussed, so determining the failure properties of graphene.Comment: 4 page
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